" There hasn’t been great success with medication on reducing a stress response. I think antidepressants are helpful for depression but not necessarily a stress response. For PTSD, which is the biggest biological outcome of an exposure to trauma, the medication approach never worked well. There’s no pharmacology that works well for PTSD: antidepressants actually don’t work at all and anti anxiety medication doesn’t seem to do any good. Rather, for PTSD, the leading approaches consist of EMDR, which is the training of eye movements as people recount the trauma. Mindfulness based stress reduction and virtual reality are other techniques that have worked as well. "