Astrocytes: an Alzheimer’s Drug Target?
Cells called astrocytes use the protein encoded by ApoE4 — a genetic mutation linked to Alzheimer’s risk — to transport cholesterol in the brain….
Cells called astrocytes use the protein encoded by ApoE4 — a genetic mutation linked to Alzheimer’s risk — to transport cholesterol in the brain….
Alzheimer’s disease affects one in 10 people over the age of 65 and one in three over the age of 85, and its global…
Ka`imi A. Sinclair has devoted her career to brain health equity in indigenous communities and to getting these communities more involved in Alzheimer’s and…
Ask most anyone involved in Alzheimer’s research what the disease’s strongest genetic risk factor is, and there will be no debate: the the E4…
Analyzing large databases of human data, scientists identified a “water pill” called bumetanide, which reduced the risk of developing Alzheimer’s for people with a…
Amid growing evidence of the neurological complications of COVID-19, which range from loss of sense of taste and smell, to ‘brain fog,’ to stroke…
Certain genes like ApoE that play an important role in the disease. ApoE’s genetic variant, known as ApoE4, is the strongest genetic risk factor…
The idea that anxiety somehow foreshadows Alzheimer’s is not new: We have seen it in, for example, 2018 findings that increased anxiety corresponded with…
While researchers have known that the ApoE4 genetic variant is the strongest genetic risk factor for Alzheimer’s and related dementias, this finding is largely…
Researchers in Germany studied the effects of ApoE4, the best known genetic factor for Alzheimer’s Disease, on the brains of 82 young adults —…
A study published this month in Neurology confirmed prior findings that a certain type of drug — anticholinergics — can be problematic, especially for…
It was never clear to researchers whether the ApoE4 gene was responsible for the early malfunction of the blood-brain barrier, a protective barrier shielding…
A new study suggests that people with two copies of ApoE4, one of the largest genetic risk factors for Alzheimer’s, have more than double…
The Alzheimer’s gene, known as ApoE4, is one of the the largest genetic risk factors for later onset Alzheimer’s disease. Carrying one copy of the…
Talk with an Alzheimer’s researcher and you’ll likely hear the same lament: Finding a treatment or cure is incredibly challenging because scientists are not…