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ApoE4 — a variant of the ApoE gene — is often called “the Alzheimer’s gene.” But what does it really mean for Alzheimer’s risk? Whether you’re curious about the science behind familial Alzheimer’s, considering genetic testing, or looking to understand test results, this guide offers a comprehensive look at what ApoE4 means for brain health — and how to take action.
ApoE helps regulate cholesterol and fat metabolism in the body. Carrying one or two copies of ApoE4 is known to increase the risk of Alzheimer’s by influencing how the brain clears beta-amyloid plaques. This gene is one of the strongest genetic risk factors for late-onset Alzheimer’s. While carrying E4 doesn’t guarantee that you will develop Alzheimer’s, understanding your genetic profile can help inform healthcare decisions and prevention strategies.
ApoE4 — a variant of the ApoE gene — is often called “the Alzheimer’s gene.” But what does it really mean for Alzheimer’s risk? Whether you’re curious about the science behind familial Alzheimer’s, considering genetic testing, or looking to understand test results, this guide offers a comprehensive look at what ApoE4 means for brain health — and how to take action.
ApoE helps regulate cholesterol and fat metabolism in the body. Carrying one or two copies of ApoE4 is known to increase the risk of Alzheimer’s by influencing how the brain clears beta-amyloid plaques. This gene is one of the strongest genetic risk factors for late-onset Alzheimer’s. While carrying E4 doesn’t guarantee that you will develop Alzheimer’s, understanding your genetic profile can help inform healthcare decisions and prevention strategies.
In this guide, we explore ApoE4’s role in Alzheimer’s, offering expert insights on genetic testing, risk assessment, and practical strategies for people who carry this variant.
You’ll find:
• The basics of ApoE4 and Alzheimer’s risk
• Implications for Alzheimer’s treatment
• Lifestyle modifications to help prevent Alzheimer’s
• Stories from ApoE4 carriers
• The latest research into genetics and Alzheimer’s