A Doctor’s and Patient’s Perspective on Living With the “Alzheimer’s Gene”

By Being Patient | June 13th, 2019

Jamie Tyrone and Dr. Marwan Sabbagh share their insights on the implications of carrying the ApoE4 genetic variant.

The interview:

Posted by Being Patient Alzheimer's on Wednesday, June 12, 2019


Jamie Tyrone discovered from a genetic test that she has a 91 percent chance of developing Alzheimer’s. In her new book, Fighting for My Life: How to Thrive in the Shadow of Alzheimer’s, Jamie shares her story, alongside medical advice from Dr. Marwan Sabbagh on what you should know about living with the Alzheimer’s gene.

ApoE4 Stores: People With the “Alzheimer’s
gene” Share Fears, Plans, Inspiration 


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Marwan Sabbagh

Dr. Marwan Sabbagh

Dr. Marwan Sabbagh is a board certified neurologist and geriatric neurologist, as well as one of the leading experts in Alzheimer’s and dementia. He is the Camille and Larry Ruvo Endowed Chair for Brain Health and the director of the Cleveland Clinic – Lou Ruvo Center for Brain Health in Las Vegas, Nevada. Previously, he served as the director of the Alzheimer’s and Memory Disorders Division at the Barrow Neurological Institute in Phoenix, Arizona, where he has also been a professor of neurology. He is a leading investigator for many national Alzheimer’s prevention and treatment trials, including Alzheimer immunotherapy studies. He is on the editorial board for Journal of Alzheimer’s Disease and BMC Neurology and editor in chief of Neurology and Therapy. He has authored and co-authored almost 300 medical and scientific articles on Alzheimer’s research.  He is the author of The Alzheimer’s Answer: Reduce Your Risk and Keep Your Brain Healthy and of The Alzheimer’s Prevention Cookbook: 100 Recipes to Boost Brain Health.

Jamie Tyrone

Jamie Tyrone

Jamie Tyrone has two copies of the ApoE4 gene, which puts her at a 91% lifetime risk of getting Alzheimer’s disease, along with 2% percent of the U.S. population. A trained nurse and former marketing executive, she is now a full-time advocate for Alzheimer’s research. She is the founder of B.A.B.E.S., “Beating Alzheimer’s by Embracing Science,” a non-profit organization that raises funds and awareness for Alzheimer’s research. She is also a founding member of WomenAgainstAlzheimer’s (WA2), a movement of women – disproportionate victims of the disease as patients and caregivers – campaigning for a new approach to finding a cure and the adoption of a national plan for the prevention and treatment of Alzheimer’s disease. She has contributed recommendations to the National Alzheimer’s Project Act (NAPA) Advisory Council, set up by the Department of Health and Human Services, on their National Plan to address the prevention, care, management and public awareness of Alzheimer’s disease.

2 thoughts on “A Doctor’s and Patient’s Perspective on Living With the “Alzheimer’s Gene”

  1. Outstanding interview! Jamie is a total inspiration and it was interesting to hear a bit about Dr. Marwan Sabbagh’s new trial looking at lifestyle.
    Thank you.

    1. My mother has dementia and advanced Alzheimer’s. I was diagnosed with Early Onset Alzheimer’s. My memory is declining! I see where my mother is at and it frightens me!!

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