Alzheimer's clinical trials, Dominic Morello
Courtesy of the author

To End Alzheimer’s, Trials Need Volunteers

By Dominic Morello | February 16th, 2021

There are more than 100 experimental Alzheimer’s treatments in the pipeline, but the majority of clinical trials for potential Alzheimer’s therapies are delayed due to enrollment shortages.

Dominic Morello, a Global Alzheimer’s Platform Foundation 2020 Citizen Scientist award nominee, shares his and his father’s story — along with a call to action and information about to find Alzheimer’s drug trials near you.

I was 23 years old when I became the primary caregiver for my dad, who was diagnosed with early-onset Alzheimer’s disease at age 54. My dad had always put family first when he was raising my two brothers and me, so when the time came, I wanted to do the same for him.

My dad was never the kind of guy to go on fishing or golfing trips – on the weekends, he was at our football and baseball games, coaching and cheering on his sons. He was the smartest person I knew, and he helped me and my brothers become the men that we are today.

My dad’s symptoms have progressed quickly in the three short years since his diagnosis. When he started to forget things that he had never forgotten before, he had to leave his job as a civil engineer. Then, as more time went on, he wasn’t able to drive. Nowadays, he cannot even cook a simple meal for himself.

Some days feel close to normal, and other days, I have to give him cues on how to do basic tasks, such as brushing his teeth. Every day since his diagnosis, I have wondered why this disease happens to people and what are its root causes.

My brothers and I grew up around Alzheimer’s. My dad’s mom and her mom had it too – I remember my grandmother slowly forgetting my name when I was a young boy. Because of this genetic history, my brothers and I are at a great risk for developing Alzheimer’s. More than 5.8 million Americans, including 400,000 Texans like my dad, are living with the disease – yet there is no cure.

This is what led us to join a clinical trial at Kerwin Research Center in Dallas. Clinical trials are the only way to find treatments and a cure for Alzheimer’s, but as much as 90 percent are delayed by slow recruitment. Every study volunteer like my dad needs a research study partner to help monitor their symptoms, so once a month, he and I make the six-hour round-trip drive from Round Rock to Dallas to help advance Alzheimer’s research.

Clinical trials are the only way to find treatments
and a cure for Alzheimer’s, but 90 percent
are delayed by slow recruitment.

My dad wanted to join a clinical trial as soon as he was diagnosed. He wanted to help other people who will go through this experience, like he has, and his mother and grandmother did before him. Alzheimer’s clinical trials need all kinds of volunteers that are 55 and older – people like my dad who are living with the disease, people like me who have a family history, and even people who have no history at all.

I am hopeful that a cure for this disease will be discovered by 2025, long before my brothers and I have to worry about it. We do not want to have to live in fear of this horrid disease being continually passed down to future generations any longer.

As a caregiver and a clinical trial volunteer, I want to do my part to raise awareness around this vital cause. Alzheimer’s is an unfair, terrible disease that turns millions of lives upside down every year – I feel very fortunate that my dad raised me to be a person who could become the head of the household when I was needed most.

My dad wanted to join a clinical trial as soon
as he was diagnosed. He wanted to help other people
who will go through this experience, like he has, and his
mother and grandmother did before him.

I am proud that my father is helping scientists in the U.S. and across the globe study this disease, and I want to continue to take care of him the way he deserves as long as I can. To end this disease, we need more volunteers to join Alzheimer’s clinical trials, including healthy people and people with memory problems.

Someday, I hope my brothers and I, and our entire generation, will think of Alzheimer’s as a thing of the past.

To find an Alzheimer’s research center working on clinical trials near you, learn more at, or search for an Alzheimer’s clinical trial you may qualify for at the National Institute on Aging’s Clinical Trials Finder.

Dominic Morello is an Electrical Distribution Outside Account Manager in Round Rock, Texas. Last year, Dominic was nominated by Kerwin Research Center for the Global Alzheimer’s Platform Foundation®’s 2020 Citizen Scientist ‘Collaborator’ Award®.

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One thought on “To End Alzheimer’s, Trials Need Volunteers

  1. I understand that in many Alzheimer’s studies they have trouble finding participants and volunteers. With the lack of volunteers for Alzheimer’s clinical trials the cure or treatment for this disease will take a long time. However, we have been trying to get our mother in a clinical trial for treatment for over a year with no success. She was diagnosed with MCI in 2019 but her condition has progressed. She has been following the Bredesen Protocol (diet and exercise) for more than a year but stopped going to the gym (Silver Sneakers) because of COVID-19. She is a non-English speaker and she is 85 years old. It’s been very frustrating to find a clinical trial that she can participate in. My mom would love to participate in one. She wants to get better. People with dementia come from different backgrounds, races and ages. We need to let a diverse population to participate in clinical trials.

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