We’re looking at ultrasound in two ways: The first way is to look at it as a delivery strategy that essentially pokes a hole in the blood-brain barrier, temporarily, so that whatever is traveling in the blood stream—whether it’s an antibody or some drug that you want to get into the brain—can be delivered more efficiently. That’s using ultrasound as a delivery strategy. The second way is also potentially exciting, since it was shown in animal models that you may not even need to deliver a drug; just opening the blood-brain barrier alone may give the cells making up the body’s immune system access to those amyloid plaques and may activate cells in the brain that could help clear amyloid by itself.
How would ultrasound technology help Alzheimer’s patients?
By Bill Fisher | October 21st, 2020