fbpx
Generic selectors
Exact matches only
Search in title
Search in content
Search in posts
Search in pages
lifestyle riskfactors dementia brainhealth research Alzheimer's

Text to speech

Researchers Discover Why Loss of Smell Indicates Alzheimer’s

By | September 27th, 2017

September 27, 2017

Have you heard of the peanut butter Alzheimer’s test? The test, reported by University of Florida researchers in 2013, measured sense of smell in each nostril by holding peanut butter under the nose. The study showed a correlation between early stages of Alzheimer’s and the inability to smell through the left nostril compared to the right. News of the test soon went viral.

The study was based on a small sample, though, and attempts to recreate the results have failed or also been based on small samples. Still, there is a lot of research that shows a failing sense of smell could be related to an early Alzheimer’s diagnosis. In a study of 1,400 seniors by the Mayo Clinic in Minnesota, researchers found that those with worse smelling abilities were 2.2 times more likely to develop dementia over the course of the three and a half year study. A new study sheds light on the link between sense of smell and Alzheimer’s disease.

A research team in Korea studied the olfactory system and the central nervous system, which includes the brain. They found beta-amyloid plaques, a biomarker of Alzheimer’s disease, in both the olfactory system and the central nervous system. Previously, beta-amyloid plaques were only found in the brain. In the study, which was conducted on mice, researchers observed that the plaques had a toxic effect on the olfactory senses after six months, even though cognitive decline was not observed until the 14-month mark.

Researchers hope that this study indicates how sense of smell could be used as an early diagnostic tool for neurodegenerative diseases.

“We have discovered an important clue to predict the onset of Alzheimer’s disease in the early stage by identifying the mechanism of beta-amyloid expression in the initial stage of Alzheimer’s that was unknown until now,” said Cheil Moon, Ph.D., an author of the study and professor at Daegu Gyeongbuk Institute of Science and Technology.

Read the full write-up here.

 

If you find our articles and interviews helpful, please consider becoming a supporting member of our community. Frustrated by the lack of an editorially independent source of information on brain health and Alzheimer’s disease, we decided to create Being Patient. We are a team of dedicated journalists covering the latest research on Alzheimer’s, bringing you access to the experts and elevating the patient perspective on what it’s like to live with dementia.

Please help support our mission.

One thought on “Researchers Discover Why Loss of Smell Indicates Alzheimer’s

  1. It seems that I have lost my sense of smell
    I am a MCI patient and I am specially anxious on the subject of my possibility of having Alzheimer already
    Sabine Farber

Leave a Reply

We are glad you have chosen to leave a comment. Please keep in mind that comments are moderated according to our comment policy.